Spirochaetes and its relation with Leptospirosis.
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LEPTOSPIROSIS

What is leptospirosis?

The Leptospira is a long, thin spiroquete with a lot of movement, that can live in the environment or as a guest in animals. There are about 200 pathogenic strains.

Leptospirosis has countless amount of symptoms, for which in consult it isn’t diagnosed properly. At the beginning of the disease is manifested by fever, headache, myalgia, chills, abdominal pain, bleeding of the skin and mucous membranes, vomiting, diarrhea and other symptoms that may cause death. Some of the most common symptoms are migraine, depression, arthritis, lumbago, vertigo, tinnitus, insomnia or sleeping too much, irritability, fibromyalgia, lupus, etc.

Once the patient is contaminated, the bacteria remains in your body for life, or until given proper treatment. Patients are frustrated during all this time , because symptoms are not cured and they aren’t diagnosed, for which there is a decrease in quality of life.

Leptospirosis disease has a worldwide distribution, humans are contaminated by contact with the urine of infected animals through wounds or abrasions in the skin or through the mucosa of the mouth, nose and eyes. Transmission from person to person very likely because when patient is questioned about their family or family history, there is always someone else in their family that presents or presented these symptoms as well.

Spirochetes and Cancer

When asked if anyone in your family has suffered or died from cancer, most of the times we find that there is family history. As is with any infection, there is a decrease in immunity and cancer can present.

Transmission

The infection is very common and in 99.99% of cases not diagnosed by the patient's family doctor. This infection has been in the world for millions of years but the bacteria have only recently discovered. Adolf Weil's described it in 1886, Hippocrates and Galen spoke of it, but Stimpson described it in 1907.

The infection occurs worldwide and can affect people who work in different environments, including people living in big cities and they do not visit the field, we believe it is transmitted by humans and various animals through: lice, fleas, bedbugs, mosquitoes , ticks, etc.. We believe that mites can also be an important transmitter and infected through the fabric covered chairs, bedding and mattresses in hotels, rats and other animals. You are advised to fumigate infected families home and check that their dogs do not have fleas, ticks or scabies. Reptiles, amphibians and birds can also be infected.

It can be transmitted to humans by cattle, pigs, horses and dogs especially when they have arthritis, rodents and any wild animal as well . It can be spread when contaminated water is ingested. Men also can be carriers and transmitters to animals or other men. Symptoms of leptospirosis vary and are nonspecific, often there are no symptoms or mild and can not make the diagnosis.

Rats jurisdictions identified in Japan before the war, as carriers, as hosts and reservoirs for infection. Leptospira is a spirochete whose cells are aerobic, which means that oxygen and water are needed to survive, they are flexible, abundant movement and are capable of causing infection. They are saprophytic which means they feed on dead organic material.. It is a bacterial disease that affects humans and animals, is caused by bacteria of the genus Leptospira, in humans causes a range of symptoms that can be mistaken for other diseases, some people may not have symptoms. We can contaminate people or animals around us and vice versa.

Species Common Infections

Dogs. - Canicula, icterohemmorragica, grippotyphosa, pomona bratislava

Cattle and deer. - Hardjobovis, pomona, grippotyphosa, icterohemorrhagiae australis, autumnalis, canicola, bataviae, hebdomadis, krematosis, tarassovi, Sejroe, bratislava

Pigs. - Pomona, bratislava, canicola, tarassovi, icterohemorrhagiae grippotyphosa, Sejroe

Sheep. - Pomona, grippotyphosa, bratislava, hardjo.

Horses. - Pomona, bratislava, canicola, icterohemorrhagiae, Sejroe.

When these animals are infected, often, no signs of infection are seen but still infect other animals.

If left untreated, it can lead to kidney damage, meningitis, liver and respiratory problems and even death. It can infect the cattle, pigs, horses, dogs, rodents and wildlife. It may be that we can not detect the symptoms of animals but continue spreading the bacteria in the urine for many years.

In southern Mexico and Central America there is a condition that affects many people and primarily attacks the kidneys, with a need for dialysis, for that reason we think that may be the Leptospirosis.

Very few cases of leptospirosis were reported in the United States and Mexico, since few cases are known, physician rarely thinks of this disease as a cause, so diagnosis is not made. The same circumstances occur Borreliosis or Lyme disease, we believe that there is a pandemic of theses diseases that doctors do not seem to recognize.

When we find a patient in our office with kidney disease we must think of leptospirosis as a possibility as it is one of the principle organs affected. ,

In a study done by Dr. Alfonso Cabezas Hildefonso isolated pathogenic leptospira were found in 10 water sources, among which there were rivers, lakes, dams, wells, streams and city wastewater . These water sources were located in different parts of the province of Pinar del Rio.

Humans transmission is through skin, mucous membranes (eyes, nose, or mouth.) Especially if we have a lesion in the skin, as well as drinking contaminated water. We observed that when a person is infected, so are on frequent occasions his parents, his children, his brothers and his or her spouse. We have also observed that sometimes the person or family have had cancer and we believe it is in the lowered immunity due to chronic infection with the spirochete.

Acute Leptospirosis

The infection appears as a fever of undetermined cause, afterwards the patient may feel better and never knew the cause for their fever. The period of incubation from when patient is infected to the time the symptoms occur is up to 28 days. In severe cases there can be liver damage and renal and cause jaundice(yellowing of the skin) and death.

Psychological changes are frequently observed in patients like depression, confusion, aggression, sometimes psychotic and schizophrenic hallucinations, personality changes and violence.

Laboratory results include: neutrophilia, thrombocytopenia, elevated albuminuria increased amylase, if there is kidney failure and urinary acidity hypocalcemia with low serum sodium , nonproductive cough with hemoptysis, and decreased the complement protein C3.

On many occasions after the acute phase, the patient goes to a chronic phase, which may have many chronic symptoms or become asymptomatic. Sometimes the onset may occur as Weil syndrome, the severity depends on the serovar of the bacteria. It is very difficult to make the diagnosis of acute leptospirosis and only physicians trained in this disease consider it a possibility and do blood work like dark field microscopy so visualize the bacteria.

Differential Diagnosis

Leptospirosis is a disease with a great amount of symptoms that makes the diagnosis that much more difficult, and can be confused with a large number of diseases:

Lyme Disease. - It's symptoms are exactly like Leptospirosis, only that sometimes there is a rash after the tick bite, but patients rarely report it. The spirochete that causes Leptospirosis is the twin sister of Treponema pallidum and Borrelia. The symptoms of the three bacteria are exactly the same, only that produces syphilis chancre, is transmitted by sex although that the other two may also be transmitted through sex.

Influenza. - Influenza fever lasts only two to three days in leptospirosis change lasts for 4 to 5 days.

Meningitis. - Leptospirosis produces many symptoms of meningitis, which is why you have to do a blood test.

Hemorrhagic Fever - Leptospirosis in its acute phase can be confused with hemorrhagic fever (Lassa, CCHF, Ebola, Marburg, etc.) and all developed similar symptoms of acute pain, nausea, bleeding, skin rash and required testing in the blood. Diarrhea is one of its symptoms which is not in leptopirosis.

Dengue. - Is a viral infection transmitted by mosquitoes but rarely fatal, the symptoms are the same as Leptospirosis and have to do blood tests to make the diagnosis.

Rift Valley Fever. - Is a viral infection that exists in Africa with identical symptoms and an incubation period of 3-6 days and be transmitted by contact with secretions from infected animals and eating raw meat and raw milk.

Legionella. - Also called Legionnaires' disease, is presented with the same symptoms but skin flush is rare.

Hepatitis. - Severe leptospirosis patients often present with jaundice.

Yellow fever. – occurs in some countries, has an incubation of 3-6 days, the symptoms are similar to Leptospirosis, spread by mosquitoes.

Malaria. - An infection transmitted by the Anopheles mosquito, but are intermittent fevers.

Chronic Leptospirosis

In this section, we will only talk about chronic Leptospirosis which there is few if any information published about it. We have seen thousands of patients but almost 100% has been the chronic form, there is no distinction of sex, age or race to contract the disease either clinical or asymptomatic.

The vast majority of patients we diagnose is when the patient already presents with chronic disease, the patient comes to the clinic with migraine, arthritis, dizziness, insomnia, chronic fatigue, facial paralysis, depression, schizophrenia, irritability, tunnel carpal syndrome, fibromyalgia, lupus, etc.. If we do not think of Spirochetes, we will send our patients to five or more specialists for the various symptoms. medical only symptomatic treatment is given and patients are never cured. In Hospital Mexico in Tijuana, we were diagnosing Lyme disease in these patients, until we started using Dark Field to see the bacteria, we realized that the vast majority of patients who we have treated have been cured is for the simple reason that the treatment is exactly the same, the same symptoms are also with the syphilis spirochete which also produces the same symptoms.

Diagnosis

I have found that the most reliable diagnosis is on dark field microscopy, the spiroquete is identified and treatment is given. We have found that in the USA and Baja California Mexico, Leptospirosis is the most common cause of these symptoms. .Treatment is given and the patient's symptoms will go away, but treatment has to be given for a minimum of 4 to 6 months, monitored by blood tests and a questionnaire of symptoms.

Contamintation or transmission

Sexual contact with an infected person, staff working with animals, contact with pets, mosquitoes, fleas, ticks etc. Rodents are a major source of leptospira as they are important reservoirs for the spirochete and transmitted directly or indirectly to human and domestic animal species. In 1998 a study was conducted in Colombia and 75 rodents found the spirochete in 62 of them. This finding is important, because the presence of rats and mice is a risk factor for Leptospira infection in animals and humans.

Prevention

An exact prevention is unknown because the disease is found in a variety of patients, different ages, sexes. people with different types of work, different economic status, different races, different age and education. The only prevention is treating patients infected as to decrease the transmission.

We must control rodents that are in or around our house, but many people are contaminated by flea bites, lice, mosquitoes, ticks, etc.. when a patient comes to our office asked the family if you have symptoms and 60% about the family also has symptoms. We recommend spraying the house every 6 months to avoid contamination of patients who are in treatment and there is a possibility that other people who are not in treatment, also contaminated and contaminating the patients.

Prognosis

Fatalities can sometimes occur with acute infection of Leptospirosis, but it is more common to find the patient in their chronic stage with longstanding symptoms like bone pain, migraines, neck pain. Symptoms have increased for which they seek medical attention. Patient usually have seen many doctors without a complete cure or diagnosis, telling them the cause is stress or give them symptomatic treatment and send them home.

Treatment

Patients should be treated with antibiotics, penicillins, clarythromicin, tetracycline’s. if symptoms are severe, in some cases hospitalization is required to administer intravenous antibiotics. . Oral treatment should be 4 to 6 months until symptoms subside and monitored with a monthly questionnaire. Many articles refer treatment with doxicicline, but I have found very little results with this antibiotic.

Conclusions

The physician should try to look fo Leptospirosis for the countless symptoms that we see in our practice. The most common symptoms are migraine, depression, arthritis, lumbago, vertigo, tinnitus, insomnia or sleeping too much, irritability, fibromyalgia, lupus, etc.

If you locate a laboratory doctor that does the dark field for Leptospirosis diagnosis can be made within 10 and effective treatment can be given.

Our Medical Center is among the few places in the world where a patient with Migraine, arthritis, chronic low back pain and facial paralysis can be cured with normal medicines that are bought in pharmacy.

Carla, has suffered 6 years with migraine.

Rene, 4 years with rheumatoid arthritis.

Florina, 3 years with Lupus.

Irene, diagnosed by fibromyalgia.

About Us

More than 20 years of experience curing patients

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Dr. Manuel R. Lazo

Medical Director

Hi, I am Dr. Manuel Lazo, Hospital Mexico’ s medical director. We have been treating patients for over 20 years, and seen that the traditional treatments do not cure, but instead only calms the symptoms for a while, as the disease keeps progressing and the medications are not only expensive but they can have horrible side effects.

Our Hospital is one of the few places in the world where patients with migraine, arthritis, lower back pain and facial paralysis could be cured.

About our treatment

When you come here for consult, we do dark field microscopy in which we look for spirochaetes in your blood.

We take away your symptoms and cure your disease with antibiotics, depending on the patient and severity of the problem. We do not use natural or “alternative” medicine, only antibiotics which can be purchased at a pharmacy.

Contact us!!

The location of Hospital Mexico in Tijuana is strategic as it is just few steps from the International Border, you can park your car on the US side and walk across to Tijuana arriving at the hospital in a few minutes.

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Hospital Mexico.
9077 Ave. de la Amistad, Colonia Federal
Tijuana, B. C., México